蘇宏基  副教授

 

 

 

 

聯絡方式

研究室:(03)-863-3581
實驗室:(03)-863-3582

辦公室

理D410

Email

hcshu@mail.ndhu.edu.tw

Office Hour

禮拜四 14:00-16:00

 

  實驗室個別網頁網址

 

  主要學歷

                    
臺灣大學學士、碩士

瑞典隆德大學化學中心生物技術博士

清華大學博士後研究

教育部公費留學
 

  研究方向

 

1.          新自動化分析系統如使用酵素與抗體之序列注入分析(sequential injection analysis, SIA)分析有機磷農藥與濫用藥物甲基安非他命與嗎啡等研究

2.          生物感測器(biosensor)之研究如使用碳粉(carbon paste)與黏粒(clay)之化學修飾酵素抗體電極分析有機磷農藥與濫用藥物

3.          使用親合性免疫技術與液相層析質譜法(APCI,ESI)分析有機污染物與藥物殘留
 

  學術著作

1.          A reagentless amperometric electrode based on carbon paste, chemically modified with D-lactate dehydrogenase, NAD+, and mediator containing polymer for D-lactic acid analysis. Biotechnology and Bioengineering, (1995) 46, 270-279

 

2.          Flow binding assay using sequential injection analysis. For bioprocess monitoring. Journal Chinese Chemical Society (2000) in press 

 

3.          Continuous Analysis of Urea in Blood by Immobilized Urease using a Conductive Biosensor. Journal Chinese Chemical Society (2000) revised manuscript submitted

 

4.          H-C.Shu, N-P. Wu (2001) A Chemically modified carbon paste electrode with D-lactate dehydrogenase and alanine aminotransferase enzyme sequences for D-lactic acid analysis. Talanta. 54, 361-368. (SCI)

 

5.          Y-S Chen, S-P Lu, H-C.Shu, (2001) Determination of organophosphate and Carbamate Pesticides Based on Amperometric Biosensor. Chemistry (The Chinese Chem. Soc., Taiwan China). 59,273-278.

 

6.          H-C Shu, N-P. Wu (2000) Continuous Analysis of Urea in Blood by Immobilized Urease using a Conductive Biosensor. J. Chinese Chemical Society 47,987-991. (SCI)

 

7.          H-C. Shu, Y-C. Ling (2000) Flow Binding Assay using Sequential Injection Analysis for Bioprocess Monitoring. J. Chinese Chemical Society 47,979-986. (SCI)

 

8.          H-C Shu, S-P Lu, S-L Lee, (2004) A biosensor based on a polyaniline/perfluorosulfonated ionomer carbon paste electrode for ammonium ion and urea analysis. Manuscript will be submitted to Anal. Chim. Acta

 

9.          H-C Shu, S-W Chung, (2004) Trace Analysis of Organophosphorous Pesticides Based on the Inhibition of Acetylcholinesterase from Fly Head Using Sequential Injection Analysis. Manuscript will be submitted to Anal. Chim. Acta

 

10.  H-C Shu, J-S Chen, Z-M Yang, (2004) Automatic Immuno-affinity Sequential Injection electrospray Mass Spectrometry (SI-ESI-MS) for D-methamphetamine determination in Urine. Manuscript in preparation.

 

11.   Hun-Chi Shu, S-I Lin, (2004) “Determination of Organophosphate and Carbamate Pesticides Based on Immobilized Acetylcholinesterase Inhibition Using Sequential Injection Analysis. Manuscript in preparation.

 

12.   H-C.Shu, N-P. Wu, Y-S Chen (2004)An Amperometric Carbon Paste Electrode, Chemically Modified with Acetylcholinestease, Choline Oxidase and Peroxidase for Acetylcholine, Choline Analysis. Manuscript in preparation.

 

13. H-C.Shu, C-Y Peng. (2004) Determination of Acetylcholine, Choline using Liquid Chromatography with Chemically Modified Carbon Paste Tri-enzyme Biosensor. Manuscript in preparation.

 

14.   H-C. Shu, Y-C. Ling (1995) A new style of flow injection analysis-sequential injection analysis. Chemistry (The Chinese Chem. Soc., Taiwan China) Dec. 53, 424-431.

 

15.   H-C. Shu, L. Gorton, B. Persson, B. Mattiasson. (1995) A reagentless amperometric electrode based on carbon paste, chemically modified with D-lactate dehydrogenase, NAD+, and mediator containing polymer for D-lactic acid analysis. II. On-line monitoring of a fermentation process. Biotechnology and Bioengineering 46, 280-284. (SCI)

 

16.   H-C. Shu, B. Mattiasson, B. Persson, G. Nagy, L. Gorton, S. Sahni, L. Geng, L. Boguslavsky and T. Skotheim. (1995) A reagentless amperometric electrode based on carbon paste, chemically modified with D-lactate dehydrogenase, NAD+, and mediator containing polymer for D-lactic acid analysis. I. Construction, Composition, and Characterization. Biotechnology and Bioengineering, 46, 270-279. (SCI)

 

17.   H-C. Shu, H. Hakanson, B. Mattiasson. (1995) On-line monitoring of D-lacticacid during a fermentation process using immobilized D-lactate dehydrogenase in a sequential injection analysis system. Analytica Chimica Acta,300, 277-285. (SCI)

 

18. H-C. Shu, D. Guoqiang, R. Kaul, and B. Mattiasson. (1994) Purification of Dlactate dehydrogenase from Leuconostoc mesenteroides ssp. cremoris using a sequential precipitation procedure. Journal of Biotechnology 34, 1-11. (SCI)

 

19.   H-C. Shu, H. Hakanson, B. Mattiasson. (1993) D-lactic acid in pork as a freshness indicator monitored by immobilized D-lactate dehydrogenase using sequential injection analysis. Analytica Chimica Acta, 283, 727-737. (SCI)

 

20.   H-C. Tseng, H-C. Shu. S-J. Lu, W-L. Chen and B-J. Chen. (1991) The study on sulfamethazine residue in mule duck (II) The effects of dietary supplementation and processing treatments. Memoirs of College of Agriculture National Taiwan University. Vol. 31, No 3, 46-57.

 

21.   H-C. Shu, H-C. Tseng, S-J. Lu, W-L. Chen and B-J. Chen. (1991) The study on sulfamethazine residue in mule duck (I) The effects of intravenous injection and oral administration. Memoirs of College of Agriculture National Taiwan University. Vol. 31, No. 3. 52-60.