Yen-Peng Ho

Professor,  Analytical Chemistry

Phone: 03-8633591 (O) 03-8633592 (Lab)

Fax: 03-863-3570 

Room:  D418 science building. 

Home Page   

E-mail: ypho@mail.ndhu.edu.tw

office hour: 10:00-12:00, Tuesday

National Dong Hwa University, Shou-Feng, Hualien, 974,  Taiwan

                                                   

  • Education

1991-1996: Ph. D. PhysicalChemistry, Case Western Reserve Univ. Cleveland, OH, USA

1982-1986: Bachelor degree of National Chung-Hsing University, Taichung, Taiwan

　

  • Experience

National Dong-Hwa University, department of chemistry, Professor 2007-

National Dong-Hwa University, department of chemistry, Associate Professor 2003-2007

National Dong-Hwa University, department of chemistry, Assistant Professor 1999-2003

University of Maryland, Maryland, USA, Research Associate 1997-1999

Colorado School of Mines, Golden, CO,USA, Research Associate 1996-1997
　

  • Research Interests

Mass spectrometry

Bioanalytical Chemistry
　

  • Patent

Use of Matrices Comprising Liquids and Light Absorbing Particles for Analysis of Microorganisms by Laser Desorption Mass Spectrometry USA5948610

　

  • Selected Publications

    　

    1. Li, Y.-Z.; Ho, Y.-P.; Chen, S.-T.; Chiou, T.-W.; Li, Z.-S.; Shiuan, D. “Proteomic comparative analysis of pathogenic strain 232 and avirulent strain J of Mycoplasma hyopneumoniae”Biochemsitry-Moscow 2009, 74 , 215-220.
    2. Ho, Y.-P.* and Reddy, M. “Mass spectrometry-based approaches for the detection of proteins of Staphylococcus species”Infectious Disorders-Drug Targets 2008, 8, 166-182. (Invited review article).
    3. Reddy, p. M.; Ho, Y.-P.*; Shanker K.; Rohini, R.; Ravinder, V.* “Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde” European Journal of Medicinal Chemistry 2009, 44, 2621-2625.

    4. Rohini, R.; Shanker, K.; Reddy, P. M.; Ho, Y.-P*.; Ravinder, V., Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: A new class of antimicrobial agents. European Journal of Medicinal Chemistry 2009, 44, 3330–3339.

    5. Shanker K.; Rohini, R.; Ravinder, V.*; Reddy, P. M.; Ho, Y.-P.* “Ru(II) complexes of N4 and N2O2 macrocyclic Schiff base ligands: Their antibacterial and antifungal studies”Spectrochimica Acta Part A 2009, 73, 205–211.

    6. Ho, Y.-P.* ; Reddy, M.; Chen, C.-T. and Lo, A. A.-L. “Applications of mass spectrometry in microbial forensics”Forensic Science Review 2009, 21, 25-50. (invited review article)

    7. Sun, M.-C.; Chen, C.-D.; Huang, Y.-S.; Wu, Z-S. and Ho, Y.-P.* “Matrix Assisted Laser Desorption/Ionization-MS-Based Relative Quantification of Peptides and Proteins using Iodoacetamide and N-Methyliodoacetamide as Labeling Reagents” J. Sep. Sci. 2008, 31, 538-547.

    8. Chang, C.-C.;Chen, P.-H.; Chu, H.-L.; Lee, T.-C.; Chou, C.-C.; Chao, J.-I.; Su, C.-Y.; Chen, J.-S., J.-S.; Tsai, C.-M.; Ho, Y.-P.; Sun, K.-W.; Cheng, C.-W.; Chen, F.-R. “Laser induced popcornlike conformational transition of nanodiamond as a nanoknife” Appl. Phys Lett. 2008, 93, 033905.

    9. Liu, K.-K.; Chen, M.-F.; Chen, P.-Y.; Lee, T.; Cheng, C.-L.; Chang, C.-C.; Ho, Y.-P.; Chao, J.-I. “Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond” Nanotechnology, 2008, 19, 205102.

    10. Hu, A.; Lo, A. A.-L.; Chen, C.-T.; Lin, K.-C.; Ho, Y.-P.* “Identifying Bacterial Species using Electrophoresis–Mass Spectrometry and SEQUEST with an Empirical Scoring Function”Electrophoresis. 2007, 28, 1387-1392.

    11. Yang, M.-W.; Chen, L.-T.; Yang, Y.-C.*; Ho, Y.-P.* “Determining the Relative Bond Dissociation Energies of the Sodium Salts of Amino Acids by Mass Spectrometry and the Kinetic Method”J. Mass Spectrom. 2007, 42, 542-544.

    12. Ho, Y.-P.; Yang, M.-W.; Chen, L.-T.; Yang, Y.-C.* “Relative Calcium Binding Strengths of Amino Acids Determined Using the Kinetic Method”Rapid Commun. Mass Spectrom. 2007, 21, 1083-1089.

    13. Chang, C.-C.; Chao, J.-I.; Ho, Y.-P. ; Sun, K.-W.; Cheng, C.-L. “Nano-manipulation on cancer cells by protein-nanodiamond complex” Biophys. J. 2007, 332A-332A Suppl. S 14. Hu, A.; Chen, C.-T.;Tsai, P.-J.; Ho, Y.-P.* “Using Capillary Electrophoresis–Selective Tandem Mass Spectrometry to Identify Pathogens in Clinical Samples”Anal. Chem. 2006, 78, 5124-5133.

    14. Lo, A. A.-L.; Hu, A.; Ho, Y.-P.* “Identification of Microbial Mixtures by LC-Selective Proteotypic-peptide Analysis (SPA)”J. Mass Spectrom. 2006, 41, 1049-1060.

    15. Hu, A.; Tsai, P.-J.; Ho, Y.-P.* “Identification of Microbial Mixtures by Capillary Electrophoresis/Selective Tandem Mass Spectrometry”Anal. Chem. 2005, 77, 1488-1495.

    16. Lin, S.-S.; Wu, C.-H.; Sun, M.-C.; Sun, C.-M.; Ho, Y.-P.* Microwave-Assisted Enzyme-Catalyzed Reactions in Various Solvent Systems J. Am. Soc. Mass Spectrom. 2005, 16, 581-588. 

    17. Chang, C.-C.; Lin, P.-Y.; Yeh, X.-C.; Deng, K.-H.; Ho, Y.-P.; Kan L.-S. Protein folding stabilizing time measurement: A direct folding process and three-dimensional random walk simulation Biochem. Biophys. Research Commun. 2005, 328, 845–850

    18. Wang, Y.F.; Ho, M.-Y.; Ho, Y.-P.* Using mass spectrometry to probe the subtle differences in conformations of several different cytochromes c in aqueous and methanol solutions J. Mass Spectrom. 2004 , 39, 1523-1570.